The
gastrointestinal (GI) tract is the site for the
ingestion, digestion and
absorption of nutrients. It is divided in the the
upper and
lower GI tracts.
The
lower GI tract is the site for final
chemical digestion,
absorption and
defecation. It begins at the opening to the
small intestine and ends at the
anus.
Small intestine
The
small intestine is the site for final
chemical digestion and the
absorption of nutrients and some
water. It has three sections: the
duodenum,
jejunum and
ileum. The
duodenum is the most
proximal part, connecting to the
stomach, and the
ileum is the most
distal and connects to the
large intestine.
The lining of the
small intestine has a very large surface area due to modifications to its
mucosa. The walls of the
small intestine are folded in large circular folds. The surface of the folds is covered in
villi, finger-like
projections of the mucosa. The epithelial
cells of the
villi (called
brush border cells) have numerous cellular
projections called
microvilli.
Movement
Segmentation is a special type of peristalsis in the
small intestine that causes the mixing and slow forward movement of
chyme.
- Segmental movements repeat several times a minute
- Rhythm-generating cells in the walls of the small intestine cause alternating contractions of adjoining
sections
Digestion
Final
chemical digestion occurs in the
duodenum
Mechanical digestion of fats occurs
A salt and
mucus secretion protects and lubricates the lining of the
small intestine while providing
hydrolysis enzymes with a
water supply
Absorption
Large intestine
The
large intestine (colon) is the final site for the body to recover materials from ingested food before
defecation. The entry to the
large intestine is controlled by a one-way sphincter called the
ileocecal valve, which is relaxed by the
hormone gastrin when a new meal enters the
stomach. Indigestible food residues, unabsorbed
bile salts and fluids make up the
chyme entering the
large intestine.
The
cecum is a small pouch for the storage of feces immediately after the
ileocecal valve. The
ascending colon travels superiorly from the
cecum to behind the
liver, where it turns to travel
medially across the abdomen as the
transverse colon. Once the
colon has reached the other side of the body, it curves downwards and travels
inferiorly as the
descending colon. The
sigmoid colon is the final section of the
colon, curving medially towards the
rectum; the storage site for feces before
defecation.
Movement
Small pouch-like segments of the
colon (
haustra) contract in slow, rhythmic movements called
haustral churning
A few times a day
mass movements contract the ascending and
transverse colon simultaneously
Defecation is stimulated when the
stretch receptors in the
rectum are activated
The
mucosa of the
large intestine secretes an alkaline mucous to protect itself. The
mucosa is
secreted in response to
mechanical and
chemical stimulation.
Absorption