Algonquin College
3.1 - The Cellular Environment
The selectively permeable cell membrane is surrounded on both sides by a solution containing water as a solvent and many dissolved solutes. It is composed of a phospholipid bilayer with many embedded molecules such as glycolipids, cholesterol and proteins of various types. The bilayer and its embedded molecules maintain a delicate balance between the extracellular and intracellular fluids.

To maintain homeostasis in the cell, the levels of solutes in the ICF and ECF must remain relatively constant. The permeability of the plasma membrane is regulated to maintain this balance of solutes. Changes in the permeability alter the transport of substances across the plasma membrane.